When choosing or editing a gaming or anime PFP, focus on a strong silhouette...

https://purepfp.com/why-bold-game-characters-remain-recognisable-in-tiny-profile-icons/

When choosing or editing a gaming or anime PFP, focus on a strong silhouette and high contrast so it stays clear even small and round. Crop tightly around the face and keep the background simple to avoid clutter